劉維屏----博士， 現(xiàn)任浙江大學(xué)環(huán)境與資學(xué)院院長(zhǎng)

主講人/Speaker：劉維屏,教授，浙江大學(xué)環(huán)境健康研究所所長(zhǎng)

Weiping LIU, Professor, the director of the Environmental Health Research Institute, Zhejiang University

劉維屏，教授，現(xiàn)任浙江大學(xué)環(huán)境健康研究所所長(zhǎng)。曾任浙江大學(xué)環(huán)境科學(xué)研究中心主任、環(huán)境與資源學(xué)院院長(zhǎng)。浙江大學(xué)獲學(xué)士和碩士學(xué)位，日本東京農(nóng)業(yè)大學(xué)博士學(xué)位。2002年國(guó)家杰出青年基金獲得者，2006年教育部“創(chuàng)新團(tuán)隊(duì)”帶頭人，浙江省“錢江學(xué)者”和浙江大學(xué)“求是學(xué)者”特聘教授。兼任中國(guó)環(huán)境科學(xué)學(xué)會(huì)理事，中國(guó)化學(xué)會(huì)環(huán)境化學(xué)分會(huì)、中國(guó)環(huán)境科學(xué)學(xué)會(huì)環(huán)境化學(xué)專業(yè)委員會(huì)委員和持久性有機(jī)污染物專業(yè)委員會(huì)委員。是生態(tài)毒理學(xué)報(bào)、農(nóng)藥學(xué)學(xué)報(bào)的副主編，Sci. Total Environ.、Ecotoxic. Environ. Safety、Chirality及環(huán)境工程學(xué)報(bào)、環(huán)境化學(xué)等的編委。

主要從事環(huán)境污染與健康方面的研究，特別是環(huán)境有機(jī)污染物的化學(xué)結(jié)構(gòu)多樣性與環(huán)境風(fēng)險(xiǎn)差異性研究。主持了國(guó)家重點(diǎn)基礎(chǔ)研究“973”和國(guó)家高科技“863”課題，國(guó)家自然科學(xué)基金杰出青年基金、重大國(guó)際合作項(xiàng)目、重大科研儀器項(xiàng)目、重點(diǎn)項(xiàng)目等國(guó)家級(jí)課題20余項(xiàng)。已在PNAS、EST等學(xué)術(shù)期刊發(fā)表論文300余篇，被引19000余次（其中SCI引用14000余次，H因子65，2014年以來(lái)均為愛(ài)思唯爾的Scopus數(shù)據(jù)庫(kù)世界高被引學(xué)者和斯坦福大學(xué)公開(kāi)發(fā)布的“世界引用最多的前10萬(wàn)名學(xué)者”之一）；出版專著教材5部（其中英文2部）；獲省部科技（教學(xué)成果）一等獎(jiǎng)3項(xiàng)。指導(dǎo)的博士研究生，2人分獲2002年“全國(guó)百篇優(yōu)秀博士學(xué)位論文”和2003年“全國(guó)百篇優(yōu)秀博士學(xué)位論文”提名論文，有2人獲美國(guó)化學(xué)會(huì)頒發(fā)的杰出青年研究獎(jiǎng)。2012年遴選為美國(guó)科學(xué)促進(jìn)會(huì)會(huì)士（AAAS Fellow）。

報(bào)告題目/Title:

Enantioselectivity in Environmental Process and Toxicology of Chiral Contaminants

環(huán)境過(guò)程中手性污染物的對(duì)映選擇性與毒理學(xué)

講座摘要/Abstract:

The speed at which new chemicals are introduced into the market is accelerating due to the rapid urbanization and industrialization worldwide. Many organic pollutants have structural diversity, such as congener, isomer and especial enantiomers. The significance of molecular chirality is widely recognized in life sciences. Enantiomers of the same compound have identical physical-chemical properties and thus appear as a single compound in standard analysis. For economic reasons, chiral pesticides are primarily used as mixtures of enantiomers, or racemates. However, enantiomers are known to selectively interact with biological systems that are usually enantioselective and may behave as drastically different compounds. Many of organic chemicals are agricultural chemicals, including but not limited to synthetic pyrethroids, organophosphates, acylanilides, phenoxypropanoic acid and imidazolinones. They are typically used in their racemic form. Unfortunately, they exhibit enantioselective behavior during agricultural use. Therefore, these compounds may pose enantioselective ecological threats to non-target organisms and/or humans, affecting the safety of food chain and even the entire ecosystem. Therefore, the toxicity of chiral pollutants has gained much attention in the academia in the recent years. Thus, it is necessary to investigate the relationships between enantioselective environmental process and toxicology of the aforementioned chiral compounds during environmental risk assessment, which has been the main focus of my research group in the past 20 years.